Articles: nerve-block.
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Acta Anaesthesiol Scand · Mar 2004
Case ReportsApplication of a mandibular nerve block using an indwelling catheter for intractable cancer pain.
We report a case in which a mandibular nerve block using an indwelling catheter was employed for pain management in a terminal case of orofacial cancer. The patient was a 74-year-old female weighing 27 kg. She had a 27-month history of mouth floor and tongue cancer. ⋯ Second, a neurolytic block was applied to the mandibular nerve through the catheter. After the neurolytic block, the total dosage of morphine and diclofenac remained unchanged for 2 months. We conclude from the present case that this technique is an excellent means of obtaining long-term pain control in patients with intractable orofacial cancer pain.
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Acta Anaesthesiol Scand · Mar 2004
Tetrodotoxin-induced conduction blockade is prolonged by hyaluronic acid with and without bupivacaine.
In isolated nerves, tetrodotoxin (TTX) blocks nerve conduction longer than bupivacaine. In vivo, however, both substances block nerve conduction to an equal duration, presumably because the hydrophilic TTX binds only weakly to the perineural tissue. High molecular weight hyaluronic acid (HA) prolongs the action of local anaesthetics several-fold. We tested whether admixture of HA enhances the binding of TTX to the perineural tissue and thus induces an ultra-long conduction block after a single application. ⋯ Both HA and HA/bupivacaine prolong the TTX-induced conduction blockade of the aortic nerve of rabbits in vivo. No signs of neurotoxicity were observed.
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Reg Anesth Pain Med · Mar 2004
Comment Letter Case ReportsPerineural catheter placement: another potential complication.