Articles: chronic.
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Bronchiectasis PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: To evaluate the effects of treatment with inhaled tobramycin in patients with non-CF bronchiectasis (BQ) considering the eradication of Pseudomona aeruginosa in sputum, changes in sputum and lung function. ⋯ The following authors have nothing to disclose: Georgina Gramblicka, María Sosa, Gabriela Tabaj, María Gallardo, Valeria Morandi, Maria Laura Grodnitzky, Luciano Peyrano, Daniela Visentini, Patricia MalamudNo Product/Research Disclosure Information.
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ILD Case Report Posters ISESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: Wegener's granulomatosis (WG) is a systemic vasculitis that usually involves the lungs, upper respiratory tract and kidneys. Histological manifestations in the lung are typically characterized by necrotizing granulomatous inflammation alongwith extensive parenchymal necrosis and necrotizing vasculitis. Several histological variants have been recognized and are characterized by bronchocentric inflammation, marked eosinophil infiltrate, alveolar hemorrhage or interstitial fibrosis. A more uncommon variant of Wegener's is a "BOOP-like" variant primarily consisting of bronchiolitis obliterans-organizing pneumonia like fibrosis; only 16 such cases have been described in the literature to date. ⋯ The following authors have nothing to disclose: Deepankar Sharma, Neil AggarwalNo Product/Research Disclosure Information.
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Reg Anesth Pain Med · Mar 2014
Case ReportsDyskinesia Caused by Ziconotide-Baclofen Combination in an Adolescent Affected by Cerebral Palsy.
To report on the first case of ziconotide-induced dyskinesia. Ziconotide, a synthetic peptide analogue of the ω-conotoxin MVIIA that blocks selectively N-type voltage-sensitive calcium channels, has been used in intrathecal administration for 30 years. Ziconotide is a drug of choice for chronic pain because of its efficacy and flexibility because it can substitute or complement other intrathecal therapies including morphine or baclofen. Whereas substantial information is available regarding its efficacy, systematic data regarding the safety of ziconotide remain scant. The adverse reactions to ziconotide described so far regard only the coordination and execution of intentional movements. ⋯ An analysis of the signaling pathways of baclofen and ziconotide revealed a possible drug interaction that allowed ziconotide to trigger dyskinesia.
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Reg Anesth Pain Med · Mar 2014
A Prospective Validation of Biplanar Ultrasound Imaging for C5-C6 Cervical Medial Branch Blocks.
Ultrasound (US) guidance offers an alternative to fluoroscopy for medial branch blocks of the upper cervical spine, but it may be less accurate for blocks at the C5 and C6 levels. We hypothesized that a modified technique using biplanar US imaging would facilitate level identification and provide greater accuracy for the lower cervical spine. ⋯ Ultrasound guidance using a biplanar approach is a reliable imaging modality for C5 and C6 medial branch blocks.
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Randomized Controlled Trial Multicenter Study
The relationship between hypophosphataemia and outcomes during low-intensity and high-intensity continuous renal replacement therapy.
To identify risk factors for development of hypophosphataemia in patients treated with two different intensities of continuous renal replacement therapy (CRRT) and to assess the independent association of hypophosphataemia with major clinical outcomes. ⋯ Hypophosphataemia is common during CRRT and its incidence increases with greater CRRT intensity. Hypophosphataemia is not a robust independent predictor of mortality. Its greater incidence in the higher intensity CRRT arm of the Randomised Evaluation of Normal vs Augmented Level trial does not explain the lack of improved outcomes with such treatment.