Articles: chronic.
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Chronic
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Am. J. Respir. Crit. Care Med. · Jan 2014
Impact of Forced Vital Capacity Loss on Survival After the Onset of Chronic Lung Allograft Dysfunction.
Emerging evidence suggests a restrictive phenotype of chronic lung allograft dysfunction (CLAD) exists; however, the optimal approach to its diagnosis and clinical significance is uncertain. ⋯ At CLAD onset, a subset of patients demonstrating physiology more suggestive of restriction experience worse clinical outcomes. Further study of the biologic mechanisms underlying CLAD phenotypes is critical to improving long-term survival after lung transplantation.