Articles: covid-19.
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Emerg Med Australas · Feb 2025
Observational StudyImpact of the Astra Zeneca COVID-19 vaccine on an emergency department.
To assess the impact of the AstraZeneca (AZ) vaccine roll-out on an ED. Primary outcomes are ED length of stay (LOS), investigation ordering and costs. Secondary measures are compliance with the Thrombosis and Haemostasis Society of Australia and New Zealand (THANZ) Vaccine-Induced Thrombotic Thrombocytopaenia Syndrome (VITT) guidelines. ⋯ A high number of young, low acuity patients presented to the ED with AZ vaccine concerns and were associated with financial and workload implications. The quantity of ED presentations appears to be associated with vaccine administration rates. There was poor compliance with the THANZ guidelines, and they appear to have contributed to the high volume of investigations.
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Anesthesia and analgesia · Feb 2025
Observational StudyAssociation Between the Ultrasound Evaluation of Muscle Mass and Adverse Outcomes in Critically Ill Patients: A Prospective Cohort Study.
Computed tomography (CT)-derived low muscle mass is associated with adverse outcomes in critically ill patients. Muscle ultrasound is a promising strategy for quantitating muscle mass. We evaluated the association between baseline ultrasound rectus femoris cross-sectional area (RF-CSA) and intensive care unit (ICU) mortality. Secondary outcomes were the determinants of RF-CSA, and the diagnostic performance of RF-CSA after adjustment for body size. ⋯ Low baseline RF-CSA was associated with increased ICU mortality. Admission RF-CSA was lower in women, with high nutritional risk, in older subjects and with lower body size. Absolute muscle mass was significantly associated with mortality, with no significant increase in this relationship when adjusting for sex or body size.
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Epidemiological surveys have monitored chronic non-cancer pain (CNCP) and investigated associated factors in Denmark for more than 20 years. This study aimed to analyse CNCP prevalence in the Danish population from 2000 to 2023 and its associations with mental health status and loneliness. ⋯ This study demonstrated alarming trend on chronic non-cancer pain prevalence over time in Denmark. The high estimates of prevalence and related issues, such as mental health and severe loneliness deserve further investigation and prioritisation in the public health agenda.
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In contrast to abundant research on the various acute mental effects of COVID-19, the long-term influences of the pandemic are still underexplored in China owing to the paucity of assessment tools. The Pandemic Disengagement Syndrome Scale (PDSS) assesses people's social disengagement as a lasting psychological consequence in Western countries during the post-COVID-19 pandemic era. However, its generalizability across cultures is untested. ⋯ The findings indicated that disengagement syndrome may exist among Chinese people even substantially after the acute phases of the pandemic. Meanwhile, the Chinese PDSS demonstrating acceptable psychometric features can be a valid instrument to assess the syndrome. Several possible reasons for the persistence of disengagement in China are discussed.
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Acta Anaesthesiol Scand · Feb 2025
Invasive mechanical ventilation strategies, adjuvants treatments and adverse events among ICU patients with COVID-19 in Denmark.
To describe the use of invasive mechanical ventilation core strategies, adjuvant treatments and the occurrence of barotrauma and prolonged ventilation in ICU patients with COVID-19 in Denmark, retrospectively. ⋯ Lung protective ventilation and prone positioning were used in many of the Danish ICU patients with COVID-19, but barotrauma, prolonged ventilation and death occurred frequently.