Articles: function.
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DVT/PE PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Our purpose is to describe clinical presentation and diagnostic approach in 5 patients presenting with upper extremity deep vein thrombosis (UEDVT) central venous catheters (CVC)-related and pulmonary embolism after cardiac surgery ⋯ The following authors have nothing to disclose: Cleante Scarduelli, Redenta Ghirardi, Ornella Tortelli, Rino Frizzelli, Fabia Mascaro, Claudio PinziNo Product/Research Disclosure Information.
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Surgery Case Report Posters IISESSION TYPE: Case Report PosterPRESENTED ON: Sunday, March 23, 2014 at 01:15 PM - 02:15 PMINTRODUCTION: Radical manubriectomy for manubrial tumors often destabilizes one or both upper extremities, but current reconstructive techniques prevent lateral but not medial clavicular displacement. ⋯ The following authors have nothing to disclose: Eric Toloza, Kathryn Rodriguez, Christian Sobky, Lori Brown, Joseph Garrett, Christy Chai, Carla Moodie, Rajendra Bhati, Gerard Mosiello, Jonathan ZagerUse of Synthes Sternal Fixation System is not yet approved for interclavicular stabilization.
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COPD Epidemiology & Physiology PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Common techniques used to measure lung volumes may yield inaccurate results in patients with large bullae. Plethysmography may overestimate while gas dilution may underestimate functional lung volumes. Auto Smart Segmentation (SS) is used by radiation physicists to accurately map lung portions receiving radiation therapy. It uses contouring methodology to trace and accurately measure volume of contoured anatomic structures. Hypothesis. Contouring of bullae on thoracic Computed Tomography (CT) and digital subtraction of contoured volumes using SS will yield accurate lung volumes unaffected by technical limitations or patient effort. ⋯ The following authors have nothing to disclose: Basim Dubaybo, Sikandar AnsariNo Product/Research Disclosure Information.
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Critical care medicine · Mar 2014
Mice Lacking the Lectin-Like Domain of Thrombomodulin Are Protected Against Melioidosis.
Thrombomodulin is a multidomain receptor primarily expressed by vascular endothelium. The lectin-like domain of thrombomodulin has anti-inflammatory properties. In this study, we investigated the role of the thrombomodulin lectin-like domain in the host response to Gram-negative sepsis caused by Burkholderia pseudomallei, a "Tier 1" biothreat agent and the causative agent of melioidosis, a common form of community-acquired sepsis in Southeast Asia. ⋯ This study reveals for the first time a detrimental role for the thrombomodulin lectin-like domain in the host response to sepsis caused by a clinically relevant Gram-negative pathogen.
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Critical care medicine · Mar 2014
The Role of Pancreatic Ductal Secretion in Protection Against Acute Pancreatitis in Mice.
A common potentially fatal disease of the pancreas is acute pancreatitis, for which there is no treatment. Most studies of this disorder focus on the damage to acinar cells since they are assumed to be the primary target of multiple stressors affecting the pancreas. However, increasing evidence suggests that the ducts may also have a crucial role in induction of the disease. To test this hypothesis, we sought to determine the specific role of the duct in the induction of acute pancreatitis using well-established disease models and mice with deletion of the Na/H exchanger regulatory factor-1 that have selectively impaired ductal function. ⋯ Our findings provide the first direct evidence for the crucial role of ductal secretion in protecting the pancreas from acute pancreatitis and strongly suggest that improved ductal function should be an important modality in prevention and treatment of the disease.