Articles: respiratory-distress-syndrome.
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Critical care medicine · Feb 1981
Temporal responses of functional residual capacity and oxygen tension to changes in positive end-expiratory pressure.
PEEP is widely accepted as a therapy for some forms of acute respiratory failure (ARF). PEEP increases functional residual capacity (FRC), decreases intrapulmonary shunt fraction, and improves arterial oxygenation. The time required for FRC and arterial oxygen tension (PaO2) to stabilize after an adjustment in the level of PEEP is not clearly established. ⋯ After PEEP was applied, an average of 15 sec was required to increase FRC; the less compliant the lung, the more rapid the change. After PEEP was removed, FRC stabilized within an average of 22 sec. When PEEP, 25 cm H2O, was removed, arterial oxygenation decreased suddenly and substantially which suggests that PEEP, especially at higher levels, should not be discontinued, even momentarily, for nonessential maneuvers.
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Intensive care medicine · Jan 1981
Case ReportsEffect of PEEP on gas exchange, pulmonary mechanics, and hemodynamics in adult respiratory distress syndrome (ARDS).
The effect of positive end-expiratory pressure on a value resulting in maximum static effective compliance was studied in 13 artificially ventilated patients suffering from adult respiratory distress syndrome. Applying positive end-expiratory pressure in this manner resulted in improvement of oxygen delivery and left ventricular stroke work. ⋯ We conclude that the response to positive end-expiratory pressure depends on the importance of the venous admixture. Artificial ventilation with positive end-expiratory pressure on a level resulting in maximum static effective compliance is indicated in cases with high venous admixture.