Articles: critical-illness.
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Journal of critical care · Apr 2022
Observational StudyTherapeutic drug monitoring of meropenem and piperacillin-tazobactam in the Singapore critically ill population - A prospective, multi-center, observational study (BLAST 1).
To determine percentage of patients with sub-therapeutic beta-lactam exposure in our intensive care units (ICU) and to correlate target attainment with clinical outcomes. ⋯ Current dosing practices may be suboptimal for ICU patients. Beta-lactam TDM may be useful.
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Pediatr Crit Care Me · Apr 2022
Virtual Developmental Screening After Invasive Mechanical Ventilation in Children: A Prospective Cohort Pilot Study.
With decreasing PICU mortality, survivor morbidity has increased. This study aims to evaluate feasibility of virtual PICU-led follow-up of patients at risk for pediatric postintensive care syndrome. ⋯ Virtual caregiver-completed surveillance is a promising method to screen children for neurodevelopmental abnormalities following PICU hospitalization and facilitate early referral for developmental intervention, but special attention must be dedicated to families with limited resources for follow-up.
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Journal of critical care · Apr 2022
Time course of the Bioelectrical Impedance Vector Analysis and muscular ultrasound in critically ill patients.
Several different tools have been developed to integrate the clinical and biochemical nutritional evaluations in critical care patients. Aims of this study were to evaluate the changes in the Bioelectrical Impedance Vector Analysis (BIVA) and ultrasonographic features of the diaphragm (DTee) and rectus femoris (RFCSA) during the first week of ICU stay. ⋯ Body composition is significantly modified after one week of ICU stay. BIVA may be useful in the definition of hydration state, while it does not seem to track muscle mass. Different temporal trends of specific BIVA and muscle ultrasound parameters were found in patients with high or low severity of illness.
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To understand parental stressors and identify potential stress-mitigators during interfacility transfer of critically ill children. ⋯ The current study identified important parent perspectives regarding the transfer of critically ill children. We recommend that stakeholders at referral centres, transport services and accepting facilities examine their current standards regarding transport processes to ensure relevant mitigators are incorporated into their programs to improve the transport experience for critically ill children and their families.
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This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2022. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2022. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from https://link.springer.com/bookseries/8901 .