Articles: mortality.
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Critical care medicine · Feb 2006
Review Meta AnalysisOxime therapy and outcomes in human organophosphate poisoning: an evaluation using meta-analytic techniques.
The status of oximes in human organophosphate poisoning is controversial. This analysis compares the outcomes of therapy with or without oximes. ⋯ Based on the current available data on human organophosphate poisoning, oxime was associated with either a null effect or possible harm. The lack of current prospective randomized controlled trials, with appropriate patient stratification, mandates ongoing assessment of the role of oximes in organophosphate poisoning.
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Over 75% of the annual estimated 9.5 million deaths in India occur in the home, and the large majority of these do not have a certified cause. India and other developing countries urgently need reliable quantification of the causes of death. They also need better epidemiological evidence about the relevance of physical (such as blood pressure and obesity), behavioral (such as smoking, alcohol, HIV-1 risk taking, and immunization history), and biological (such as blood lipids and gene polymorphisms) measurements to the development of disease in individuals or disease rates in populations. We report here on the rationale, design, and implementation of the world's largest prospective study of the causes and correlates of mortality. ⋯ This study will reliably document not only the underlying cause of child and adult deaths but also key risk factors (behavioral, physical, environmental, and eventually, genetic). It offers a globally replicable model for reliably estimating cause-specific mortality using VA and strengthens India's flagship mortality monitoring system. Despite the misclassification that is still expected, the new cause-of-death data will be substantially better than that available previously.
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Outcome in intensive care can be categorized as mortality related or morbidity related. Mortality is an insufficient measure of ICU outcome when measured alone and length of stay may be seen as an indirect measure of morbidity related outcome. The aim of the present study was to estimate the incidence and predictive factors for intrahospitalar outcome measured by mortality and LOS in patients admitted to a surgical ICU. ⋯ In conclusion, prolonged ICU stay is more frequent in more severely ill patients at admission and it is associated with higher hospital mortality. Hospital mortality is also more frequent in patients submitted to emergent and major surgery.
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This report presents injury mortality data for 2002 using the external-cause-of-injury mortality matrix for the International Classification of Diseases, Tenth Revision (ICD-10). The external cause matrix is a detailed and comprehensive framework for tabulating and presenting injury deaths by mechanism and intent of death. Data are presented by age, sex, race, Hispanic origin, and State. In addition, trend data are shown for 1999-2002 by age, sex, and mechanism and intent of injury. This report also introduces the injury mortality diagnosis matrix. This latter is another framework that categorizes the nearly 1,200 injury diagnosis codes from ICD-10's chapter 19 according to body region and nature of the injury diagnosis information captured in the multiple-cause-of-death fields of the national mortality file. This report supplements the annual report of final mortality statistics. ⋯ Injury mortality data presented in this report using the external cause-of-injury mortality matrix for ICD-10 provide detail on the mechanism of death needed for research and other activities related to injury prevention. This report highlights the importance of multiple causes-of-death data when analyzing injury mortality--special attention is given to the issue of accuracy and completeness of information as it pertains to these data. The Centers for Disease Control and Prevention's (CDC) National Center for Health Statistics (NCHS) is involved in several ongoing projects related to the study of injury and injury mortality.