Article Notes

• Hide
  • Pearls
  • Summaries
  • Comments

pearl
1
High intraoperative FiO₂ does not significantly reduce surgical site infections.
Myles PS, Carlisle JB, Scarr B. Evidence for compromised data integrity in studies of liberal peri-operative inspired oxygen. Anaesthesia. 2019 May 1; 74 (5): 573-584.
  Daniel Jolley
pearl
1
Intravenous lidocaine improves postoperative analgesia at 4h and 24h after laparoscopic or open abdominal surgery, but not at 48h or for other surgery types.
Weibel S, Jokinen J, Pace NL et al. Efficacy and safety of intravenous lidocaine for postoperative analgesia and recovery after surgery: a systematic review with trial sequential analysis. Br J Anaesth. 2016 Jun 1; 116 (6): 770-83.
  Daniel Jolley
pearl
1
Spinal 2-chloroprocaine has pharmacokinetic advantages over low dose bupivacaine that make it a useful choice for ambulatory surgery.
Saporito A, Ceppi M, Perren A et al. Does spinal chloroprocaine pharmacokinetic profile actually translate into a clinical advantage in terms of clinical outcomes when compared to low-dose spinal bupivacaine? A systematic review and meta-analysis. J Clin Anesth. 2019 Feb 1; 52: 99-104.
  Daniel Jolley
pearl
1
Dexmedetomidine reduces perioperative stress and inflammation, while supporting surgical patients’ immune function.
Wang K, Wu M, Xu J et al. Effects of dexmedetomidine on perioperative stress, inflammation, and immune function: systematic review and meta-analysis. Br J Anaesth. 2019 Dec 1; 123 (6): 777-794.
  Daniel Jolley
pearl
1
LMA use in children with URTIs reduces cough compared to intubation, but possibly not laryngospasm, although quality of evidence is poor.
de Carvalho Ana Lygia R ALR From the Departamento de Anestesiologia., Vital RB, CCS de Lira et al. Laryngeal Mask Airway Versus Other Airway Devices for Anesthesia in Children With an Upper Respiratory Tract Infection: A Systematic Review and Meta-analysis of Respiratory Complications. Anesth. Analg. 2018 Oct 1; 127 (4): 941-950.
  Daniel Jolley
pearl
1
Intrathecal hyperbaric and isobaric bupivacaine are equally clinically effective when used for elective cesarean section, although hyperbaric has slightly faster block onset.
Sng BL, NLR Han, Leong WL et al. Hyperbaric vs. isobaric bupivacaine for spinal anaesthesia for elective caesarean section: a Cochrane systematic review. Anaesthesia. 2018 Apr 1; 73 (4): 499-511.
  Daniel Jolley
comment
1
Removing retracted and suspicious studies completely reverses the WHO 2016 recommendation for high FiO2 to reduce surgical infections. The scourge of academic misconduct continues!
Myles PS, Carlisle JB, Scarr B. Evidence for compromised data integrity in studies of liberal peri-operative inspired oxygen. Anaesthesia. 2019 May 1; 74 (5): 573-584.
  Daniel Jolley
pearl
1
Erythropoietin further reduces red blood cell transfusion in surgical patients, beyond iron therapy alone.
Kei T, Mistry N, Curley G et al. Efficacy and safety of erythropoietin and iron therapy to reduce red blood cell transfusion in surgical patients: a systematic review and meta-analysis. Can J Anaesth. 2019 Jun 1; 66 (6): 716-731.
  Daniel Jolley
pearl
1
MAC-awake of sevoflurane is modestly lower in patients with end-stage renal failure compared with normal controls.
Wu Y, Jin S, Zhang L et al. Minimum Alveolar Concentration-Awake of Sevoflurane Is Decreased in Patients With End-Stage Renal Disease. Anesth. Analg. 2019 Jan 1; 128 (1): 77-82.
  Daniel Jolley
pearl
1
Intravenous dexamethasone at all studied doses did not prolong median nerve block.
Short A, El-Boghdadly K, Clarke H et al. Effect of intravenous dexamethasone on the anaesthetic characteristics of peripheral nerve block: a double-blind, randomised controlled, dose-response volunteer study. Br J Anaesth. 2020 Jan 1; 124 (1): 92-100.
  Daniel Jolley