• S C Adiyaman, G Bengi, M Civak, M Birlik, Z Kuruuzum, C Altay, and M Soyturk.
• Department of Internal Medicine, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.
• Niger J Clin Pract. 2020 Apr 1; 23 (4): 581-585.

AbstractAdult-onset Still's disease is a systemic inflammatory disease that often presents with spiking fever, typical rash, arthritis, and serositis. However, adult-onset-Still's-disease associated liver injury and acute liver failure are rare. Herein, we report a case of acute liver injury in a 23-year-old female patient with adult-onset Still's disease. She presented to the emergency department with a high fever and sore throat. She was then admitted to the department of infectious diseases with a preliminary diagnosis of an atypical respiratory infection. After being treated with antibiotics and antiviral agents, she was discharged. A few days later, she returned to the emergency department with jaundice and was rehospitalized. This time, she was admitted to the department of gastroenterology, where she was diagnosed with adult-onset Still's disease-associated acute liver injury. Eventually, the patient responded to immunosuppressive treatment with significant clinical improvement.

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