• Rafif A Al-Ahmad, Areej A Sheerah, Khalid A Alhasan, and Jameela A Kari.
• Department of Pediatrics, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia. E-mail. rafifali33@gmail.com.
• Saudi Med J. 2020 May 1; 41 (5): 479484479-484.

ObjectivesTo evaluate the practice and attitude of pediatrics nephrologists about cinacalcet use in children.MethodsAn electronic structured questionnaire was answered by pediatric nephrologists practicing in the Kingdom of Saudi Arabia (KSA) and Gulf Council countries (GCC).ResultsA total of 42  pediatric nephrologists responded, of them, 42% used cinacalcet for young children ≤5 years of age and 79% used for children. There were wide variations in the method of administration (examples: crushed, divided, whole tablets), monitoring, doses and response definition, and follow-up. No serious complications after starting cinacalcet was observed in 50%, while 40% reported various complications, mainly hypocalcemia (70%). Cinacalcet was stopped without achieving the target parathyroid hormone in more than half (55%) of children because of intractable adverse effects (40%), poor response (30%), non-adherence (25%), or high cost (5%).ConclusionCinacalcet is used by the majority of pediatric nephrologists in KSA and GCC. A standard clinical guideline is needed to be followed by all users.

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