• World Neurosurg · Sep 2020

    Case Reports

    Spinal cord compression caused by fibroblastic reticular cell tumour (FRCT) originating from thoracic spine.

    • Baig Mirza Asfand A Department of Neurosurgery, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: asfand.mirza@nhs.net., Ravindran Visagan, Zita Reisz, Istvan Bodi, David Bell, and Gordan Grahovac.
    • Department of Neurosurgery, King's College Hospital NHS Foundation Trust, London, United Kingdom. Electronic address: asfand.mirza@nhs.net.
    • World Neurosurg. 2020 Sep 1; 141: 20-24.

    BackgroundThe authors present the first reported case of a fibroblastic reticular cell tumor (FRCT) presenting with spinal cord compression. FRCTs are the rarest subset of dendritic cell tumors, a specific group of hematologic malignancies. FRCTs reportedly behave similar to low-grade sarcomas as opposed to malignant tumors.Case DescriptionA 45-year-old female patient presented with a 2-and-a-half week history of a flu-like illness and 1 week history of lower limb imbalance. Magnetic resonance imaging revealed an extradural lesion at T3/4 compressing the spinal cord. Initially, the patient was presumed to have metastatic spinal cord compression, and she underwent a decompressive thoracic laminectomy with debulking of the lesion with follow-up adjuvant radiotherapy. However, histology identified a unique primary FRCT originating from spine, not secondary metastatic spinal cord compression. There were no histologically aggressive features likely contributing to the favorable outcome following surgery and adjuvant radiotherapy. Her postoperative recovery was unremarkable, and she recovered fully.ConclusionsAlthough rare, we report the first case of FRCT originating in the spine causing spinal cord compression. The clinical presentation of the case, histologic features of FRCT, and the treatment options are reviewed.Crown Copyright © 2020. Published by Elsevier Inc. All rights reserved.

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