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- Kuan-Hsuan Chen, Sheng-Fan Wang, Szu-Yu Wang, Yi-Ping Yang, Mong-Lien Wang, Sih-Hwa Chiou, and Yuh-Lih Chang.
- Department of Pharmacy, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
- J Chin Med Assoc. 2020 Sep 1; 83 (9): 817-821.
AbstractAs the coronavirus disease 2019 (COVID-19, also called severe acute respiratory syndrome coronavirus-2) outbreak accelerates, vigorous and diverse efforts were made in developing treatment strategies. In addition to direct acting agents, increasing evidence showed some potential adjuvant therapies with promising efficacy against COVID-19. These therapies include immunomodulators (i.e. intravenous immunoglobulin, thymosin α-1, interleukin [IL]-6, tocilizumab, cyclosporine, thalidomide, fingolimod), Chinese medicines (i.e. glycyrrhizin, baicalin, Xuebijing), anti-vascular endothelial growth factors (bevacizumab), estrogen modulating drugs, statins, and nutritional supplements (i.e. vitamins A, B, C, D, E and zinc). This article reviewed the pharmacological development of potential adjuvants for COVID-19 treatment.
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