• Masahiro Oishi, Hironori Fujisawa, Katsuhiro Tsuchiya, and Yoshio Nakajima.
• Department of Neurosurgery, Kanazawa University Hospital, Kanazawa, Ishikawa, Japan. Electronic address: ma-oishi@med.kanazawa-u.ac.jp.
• World Neurosurg. 2020 Sep 1; 141: 318-322.

BackgroundRadiation-induced spinal cord cavernous malformations (CMs) are rare pathologies compared with radiation-induced cerebral CMs. We present a case of a radiation-induced spinal cord CM developed 31 years after radiation therapy for medulloblastoma.Case DescriptionA 37-year-old man developed a symptomatic spinal hemorrhagic lesion 31 years after radiation therapy for medulloblastoma. Magnetic resonance imaging revealed an intramedullary cystic lesion with a fluid-fluid level in the C7 area. Surgery was performed leading to an unclear diagnosis. Two years later, the patient had a relapse and underwent a second operation, allowing a definitive diagnosis of radiation-induced spinal cord CM. This is believed to be the second case of de novo intramedullary CM formation following spinal radiation therapy for medulloblastoma.ConclusionsRadiation-induced spinal cord CMs should be recognized as a possible late adverse effect in patients treated with radiation therapy for medulloblastoma.Copyright © 2020 Elsevier Inc. All rights reserved.

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