• Taner Demirci, Ceyhun Varim, Ayse Demirci, Mahmut Apaydin, İlknur Öztürk Uysal, and Mustafa Ozbek.
• Department of Endocrinology and Metabolism, Sakarya University Research and Education Hospital, Sakarya, Turkey.
• J Coll Physicians Surg Pak. 2020 May 1; 30 (5): 490-492.

ObjectiveTo investigate the effects of radioactive iodine therapy (131I) on saliva production rate in the early post-treatment period.Study DesignDescriptive, analytical study. Place and Duration of Study: Department of Endocrinology, Ankara Diskapi Yildirim Beyazit Research and Education Hospital, Ankara, Turkey from January to December 2017.MethodologyA total of 40 patients, who received radioactive iodine therapy after total thyroidectomy, were included in the study. Stimulated and unstimulated saliva levels were measured before and after treatment, using a scaled and sterile plastic tube.ResultsThe study group was comprised of three males (7.5%) and 37 females (92.5%) with a mean age of 44.15 ±10.2 years (range 26-66 years). The median values of all non-stimulated saliva before and after RAI treatment were 2.0 ml / minute (1.13-2.88) and 2.0 ml / minute (1.63-4.00), respectively; and the difference was not statistically significant (p=0.11). Similarly, there were no statistically significant differences in the median values of stimulated saliva before and after RAI treatment (median=7.0 ml/min and 7.5 ml/dk, respectively; p=0.88).ConclusionRadioactive iodine treatment did not cause sialadenitis and did not affect the saliva production rates in the early post-treatment period. Key Words: Radioactive iodine, Stimulated saliva, Unstimulated saliva.

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