• Andressa Souza Cardoso, Mariana Otero Xavier, Dos Santos Costa Caroline C Center for Epidemiological Research in Nutrition and Health, University of São Paulo, Brazil., Elaine Tomasi, Juraci Almeida Cesar, Maria Cristina Gonzalez, Marlos Rodrigues Domingues, Thiago Gonzalez Barbosa-Silva, and Renata Moraes Bielemann.
• School of Nutrition, Federal University of Pelotas, Brazil. Electronic address: deessacardoso@gmail.com.
• Prev Med. 2020 Oct 1; 139: 106173.

AbstractThis study aims to measure the association between body mass index (BMI), comparing two different classifications, and mortality among community-dwelling elderly considering myopenia in Pelotas, Brazil. This is a longitudinal study started in 2014, we followed 1451 elderly people (≥ 60 years) enrolled in the "COMO VAI?" study. BMI was classified according to the World Health Organization (WHO) and the classification with specific cutoff points for older adults. Myopenia was measured by calf circumference (≤33 cm for women and ≤34 cm for men). Cox proportional-hazards models were used to test associations controlling for sociodemographic and behavioral characteristics and number of morbidities. Nearly 10% (N = 145) of the elderly died during almost three years of follow-up. We observed a L-shaped relation between BMI and mortality. Elderly with underweight had a higher mortality risk compared to those with adequate BMI in both classifications. According to the WHO classification, overweight elderly presented protection for mortality (HR: 0.58; 95% CI 0.38-0.87) when compared to those with adequate BMI. Among elderly with myopenia, overweight by WHO continued to protect against mortality, although not significantly, while those with the specific classification underweight presented a higher risk of death compared to those with normal weight (HR: 2.09; 95% CI 1.06-4.14). In conclusion the underweight increased the risk of death in community-dwelling elderly people during a follow-up of three years. The specific classification seemed to be more adequate to indicate risk of mortality in this population. Higher BMI protect against mortality when muscle mass was not considered.Copyright © 2020 Elsevier Inc. All rights reserved.

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