• Cleve Clin J Med · Jun 2020

    Review

    Glucocorticoid-induced osteoporosis: Insights for the clinician.

    • Shakaib Hayat and Marina N Magrey.
    • MetroHealth Medical Center, Cleveland, OH.
    • Cleve Clin J Med. 2020 Jun 30; 87 (7): 417-426.

    AbstractGlucocorticoids cause significant bone loss, predominantly affecting trabecular bone, with consequent fragility fractures. The risk of fractures is related to the dose and duration of glucocorticoid use, but an increased risk may be observed even at low doses and even in the first month of treatment. Steps to prevent or treat osteoporosis should be considered in all patients who take the equivalent of prednisone at a dose of 2.5 mg or more per day for 3 or more months.Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved.

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