• World Neurosurg · Sep 2020

    Review

    Updates in Chronic Subdural Hematoma: Epidemiology, Etiology, Pathogenesis, Treatment and Outcome.

    • James Feghali, Wuyang Yang, and Judy Huang.
    • Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
    • World Neurosurg. 2020 Sep 1; 141: 339-345.

    AbstractChronic subdural hematoma (CSDH) is a complex disease with an overall incidence of 1.7-20.6 per 100,000 persons per year and is more commonly encountered in the elderly population. The pathophysiologic cycle of CSDH formation and expansion involves traumatic and inflammatory components that promote the formation of membranes with permeable neovessels. Many drugs targeting different elements of this cycle are being actively investigated as potential therapeutic agents in CSDH. Burr hole craniostomy appears to be the most commonly used procedure for surgical evacuation, and outcomes are generally favorable. Recurrence can occur in 10%-20% of patients and is associated with several clinical and radiographic predictors. Middle meningeal artery embolization represents one of the latest additions to the therapeutic arsenal of cerebrovascular specialists in treating CSDH and is being critically evaluated in numerous ongoing clinical trials.Copyright © 2020 Elsevier Inc. All rights reserved.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…