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Case Reports
Two immunocompromised patients with diffuse alveolar hemorrhage as a complication of severe COVID-19.
- Christian Löffler, Juliane Mahrhold, Peter Fogarassy, Martin Beyer, and Bernhard Hellmich.
- Department of Internal Medicine, Rheumatology and Immunology, medius Klinik Kirchheim, Academic Teaching Hospital University of Tübingen, Kirchheim unter Teck, Germany. Electronic address: c.loeffler2@medius-kliniken.de.
- Chest. 2020 Nov 1; 158 (5): e215-e219.
AbstractDiffuse alveolar hemorrhage (DAH) is a severe and potentially life-threatening disease manifestation. In addition to autoimmune diseases such as antineutrophil cytoplasmic antibody-associated vasculitis and anti-glomerular basement membrane syndrome, pulmonary viral infections are known to be culprits of DAH. Health-care providers worldwide in the coronavirus disease 2019 pandemic have been confronted with an unprecedented number of viral lung infections, with great variance in symptoms and severity. Hemoptysis, the key symptom of DAH, is a rare complication. We present two cases of immunocompromised patients with rapidly developing hypoxemic respiratory failure and evidence of DAH in the context of severe acute respiratory syndrome coronavirus 2 infection.Copyright © 2020. Published by Elsevier Inc.
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