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- Margaux M McConn, Joseph T Gundy, Suzanne B Karan, and Danielle M Lindenmuth.
- From the Department of Anesthesiology and Perioperative Medicine, University of Rochester Medical Center, Rochester, New York.
- A A Pract. 2020 Jun 1; 14 (8): e01248.
AbstractMidazolam is commonly used for sedation during procedures because of its relative safety and predictability. Still, some rare undesirable medication reactions have been described. We report a case in which midazolam given before a peripheral nerve block caused acute onset dyskinetic extrapyramidal symptoms. These symptoms ultimately resolved following reversal of the midazolam with flumazenil. Given the widespread and multidisciplinary use of midazolam, practitioners should be aware of the potential for rare adverse reactions and be prepared to manage these scenarios.
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