• Muhammad Athar Sadiq, Marwa Salim Al Habsi, Sunil Kumar Nadar, Muhammad Mujtaba Shaikh, and Hafidh Aqeel BaOmar.
• Muhammad Athar Sadiq, PhD, Cardiology Unit, Department of Medicine Sultan Qaboos University Hospital Al Khoudh 123, Muscat, Oman.
• Pak J Med Sci. 2020 Jul 1; 36 (5): 1140-1142.

AbstractContrast induced neurotoxicity (CIN) is a rare complication of cardiac catheterization and re-exposure to contrast medium carries the risk of recurrent CIN. We report a case of successful contrast re-challenge in a 60-year-old female patient who developed CIN after her first procedure of coronary angiography (CAG) which resulted in symptoms of disorientation, amnesia and cortical blindness. A non-contrast enhanced CT performed four hours after the CAG was normal, however, her MRI brain scan showed scattered tiny hyper intensities in posterior occipito-temporal and parietal regions suggesting CIN. Patient's symptoms resolved completely after 72 hours. Two months later, because of persistent exertional angina, patient was successfully re-challenged with lesser amount of contrast medium with administration of hydrocortisone prior to procedure, and PCI to LAD was completed without recurrence of CIN.Copyright: © Pakistan Journal of Medical Sciences.

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