• Selcuk Yildiz and Zer TorosSemaSDepartment of Otorhinolaryngology, Head and Neck Surgery, Haydarpaşa Numune Training and Research Hospital, Istanbul, Turkey..
• Department of Otorhinolaryngology, Head and Neck Surgery, Haydarpaşa Numune Training and Research Hospital, Istanbul, Turkey.
• J Coll Physicians Surg Pak. 2020 Jun 1; 30 (6): 606-610.

ObjectiveTo evaluate the concomittant metabolic disorders, mean platelet volume (MPV), and neutrophil to lymphocyte ratio (NLR) in patients with idiopathic sudden sensorineural hearingloss (SSNHL) in comparison to healthy controls.Study DesignCase-control study.Place And Duration Of StudyDepartment of Otorhinolaryngology, Head and Neck Surgery, University of Health Sciences, Haydarpaşa Numune Training and Research Hospital, Turkey, from December 2016 to May 2019.MethodologyFifty-five patients aged 18-59 years and diagnosed with idiopathic SSNHL and 145 healthy individuals who applied for a hearing screening within the same time period (control group). Demographics, concomitant diseases, laboratory results, and outcome of pure tone audiometers were recorded. MPV and NLR were the outcome measures.ResultsThe percentage of individuals with high MPV level was 10.9% in the idiopathic SSNHL group, it was identified as 2.8% in the control group (p = 0.040). The average NLR was higher in patients with idiopathic SSNHL than control group (1.7 (1.42-2.20) and 1.5 (1.29-1.88), p = 0.004). A NLR level of 2.01 and above is associated with 2.881 times higher risk of idiopathic SSNHL (odds ratio 2.881, 95% confidence interval 1.427-5.817).ConclusionHigh MPV and NLR values are associated with idiopathic SSNHL, suggesting the role of vascular pathologies in etiology of idiopathic SSNHL. Therefore, patients with idiopathic SSNHL should undergo detailed evaluation including hematological indices. Key Words: Idiopathic sudden sensorineural hearing loss, Mean platelet volume, Neutrophil to lymphocytes ratio.

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