• Hiroshi Juri, Takahiro Tsuboyama, Seishi Kumano, Yuki Inada, Mitsuhiro Koyama, Haruhito Azuma, and Yoshifumi Narumi.
• 1 Department of Radiology, Osaka Medical College, Takatsuki, Japan.
• Br J Radiol. 2016 Jan 1; 89 (1058): 20150495.

ObjectiveTo prospectively compare the detection of bladder cancer between low-dose scans with adaptive iterative dose reduction three dimensional projection (AIDR 3D) and routine-dose scans with filtered back projection (FBP) on the excretory phase (EP) in CT urography.Methods42 patients were included. Routine- and low-dose EP were performed in each patient. Routine-dose images were reconstructed with FBP, and low-dose images were reconstructed with AIDR 3D. Two radiologists scored confidence levels for the presence or absence of bladder cancer using a 5-point scale. The CT dose index of each EP was measured, and the dose reduction was calculated.ResultsSensitivity, specificity and accuracy were 86.4%, 95.0% and 90.5% on routine-dose scans and were 86.4%, 90.0% and 88.1% on low-dose scans, respectively. There was no significant difference (p; not significant, 1.00 and 1.00, respectively). The average CT dose index was 8.07 and 2.63 mGy on routine- and low-dose scans, and the ratio of dose reduction was 67.6%.ConclusionThe detection of bladder cancer on low-dose scans with AIDR 3D is almost equal to that on routine-dose scans with FBP on the EP, with nearly 70% dose reduction.Advances In KnowledgeUsing AIDR 3D, the radiation dose may be reduced on the EP in CT urography for the detection of bladder cancer.

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