• Camilla Ribeiro Vieira, Mariana Grancieri, Martino Hércia Stampini Duarte HSD Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa, Brazil., Dionéia Evangelista César, and Roberta Ribeiro Silva Barra.
• Department of Nutrition, Universidade Federal de Alfenas, Alfenas, Brazil.
• Nutrition. 2020 Oct 1; 78: 110869.

ObjectiveThe aim of this study was to verify the effect of a beverage containing ora-pro-nobis (OPN) flour on intestinal microbiota, gastrointestinal symptoms, and anthropometric parameters in women.MethodsThis prospective, double-blinded, randomized clinical trial included 24 women volunteers. For 6 wk, the test group received a beverage supplemented with OPN, and the control group received the same beverage without OPN. Fecal microbiota were evaluated by the fluorescence in situ hybridization method. Each participant responded to a questionnaire based on the Gastrointestinal Symptom Rating Scale. The data were analyzed by Student's t test to compare the effects between treatments (P < 0.05).ResultsSupplementation with the OPN beverage reduced weight (P = 0.008), waist circumference (P = 0.010), and body fat (P = 0.000). Additionally, the treatment increased satiety (P = 0.039), reduced eructation (P = 0.038) and constipation (P = 0.017), and improved feces consistency (P = 0.017).ConclusionThe OPN flour beverage has an effect on weight reduction, body fat composition, and improvement in gastrointestinal symptoms. These results highlight the beneficial effects of ora-pro-nobis flour beverage against the development of obesity.Copyright © 2020 Elsevier Inc. All rights reserved.

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