• Wei Zhao, Jun Li, Hengwen Chen, Qingjuan Wu, Yawen Deng, and Yuqing Tan.
• Guang 'anmen Hospital, China Academy of Traditional Chinese Medicine.
• Medicine (Baltimore). 2020 Aug 7; 99 (32): e21590.

BackgroundAs one of the common cardiovascular diseases, acute myocardial infarction (AMI) is characterized by a high mortality rate, frequent complications, and a serious threat to human health and quality of life. Traditional Chinese medicine injection (TCMI) has been used clinically to treat AMI; however, there is no uniform standard for clinical treatment of AMI. The purpose of this study is to evaluate the efficacy and safety of different TCMI by using systematic review and network meta-analysis.MethodsAccording to the strategy, the authors will retrieve both 4 Chinese databases and 3 English databases by June 30, 2020. After a series of screening, randomized controlled trials will be included related to TCMI for AMI. Two researchers will use Aggregate Data Drug Information System and STATA 15.0 to analyze the data. Finally, the evidence grade of the results will be evaluated.ResultsThis study will provide a reliable evidence for the selection of TCMI therapies for AMI.ConclusionThe results of this study will provide references for evaluating the influence of different TCMI therapies for AMI, and provide decision-making references for clinical research.Osf Registration NumberDOI 10.17605/OSF.IO/FYGBT.

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