• Kojiro Kuroda, Hirotsugu Miyoshi, Takahiro Kato, Ryuji Nakamura, Toshimichi Yasuda, Kyoko Oshita, Noboru Saeki, Hiroshi Hamada, and Masashi Kawamoto.
• Department of Anesthesiology and Intensive Care, Hiroshima University Hospital, Hiroshima, Japan. Electronic address: kojiro.kuroda@gmail.com.
• J Clin Anesth. 2015 Dec 1; 27 (8): 665-7.

ObjectivesAccidental dural puncture (ADP) is known as a complication of epidural anesthesia. Although puncture site and advanced age have been reported to increase the risk of ADP, all related factors have not been fully investigated. We retrospectively investigated factors related to ADP in patients undergoing surgery.MethodsWe reviewed the records of 4107 patients who received epidural anesthesia or combined spinal-epidural anesthesia from April 2010 to March 2013 at our institution. We defined ADP as cases in which cerebrospinal fluid was obviously discharged during puncture and excluded cases in which the epidural catheter was suspected to be inserted into subarachnoid space. We investigated patient background including age, sex, height, body weight, body mass index, vertebral level of puncture site, and presence of ADP, with Student t test, a χ(2) test, and multivariable logistic regression analysis used for statistical tests and significance set at P < .05.ResultsTwenty (0.49%) of our patients had ADP. Factors significantly associated were punctures in the 10th-12th thoracic intervertebral (P = .01; odds ratio [OR], 5.19; 95% confidential interval [95% CI], 1.41-19.14) and first to third lumbar intervertebral (P = .03; OR, 5.45; 95% CI, 1.23-24.12) spaces and age (per 1-year increase, P < .01; OR, 1.04; 95% CI, 1.01-1.07).DiscussionAccidental dural puncture occurred in 0.49% of all surgical patients undergoing epidural anesthesia and was significantly related to those who received a puncture in lower thoracic and lumbar intervertebral spaces, whereas age was also an independent factor.Copyright © 2015 Elsevier Inc. All rights reserved.

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