• Li-Yu Tao, Yi-Ru Wang, Yi-Fan Zhang, Ping Liu, and Xiao-Hong Chen.
• Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine.
• Medicine (Baltimore). 2020 Aug 28; 99 (35): e21955.

BackgroundHypertension is a clinically common cardiovascular disease, resulting in many complications. Omega-3 might be beneficial in lowering blood pressure. This protocol will be performed to evaluate the effects of omega-3 on blood pressure in hypertensive patients.MethodsWe will search both the electronical databases and paper-published journals. Endnote software will be used to complete study screening and data extraction by 2 reviewers independently. Review Manager software will be used to synthesize the data. The primary outcomes are systolic blood pressure and diastolic blood pressure. Secondary outcome is the adverse effects.ResultsThe results of this study will propose a trustworthy evidence to evaluate the effects of omega-3 on blood pressure of hypertensive patients.ConclusionThe conclusion of our systematic review will reply whether omega-3 is an effectual intervention to lower blood pressure of hypertensive patients.EthicsThis review does not require ethical approval because all of the data analyzed in this review have been published.Registration NumberINPLASY202070103 (DOI number: 10.37766/inplasy2020.7.0103).

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