• Nanyang Liu, Tingting Zhang, Lina Ma, Huican Wang, and Hao Li.
• Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing.
• Medicine (Baltimore). 2020 Aug 14; 99 (33): e21709e21709.

BackgroundThe 2019 Coronavirus Disease (COVID-19) pandemic has threatened millions of people worldwide. Growing evidence suggests that the ABO blood type contributed to the susceptibility of COVID-19, but the results are controversial. The major objective of this systematic review and meta-analysis study is to investigate the impact of ABO blood group on COVID-19 pneumonia.MethodsTwo independent reviewers searches the databases of the China Biology Medicine disc, China National Knowledge Infrastructure, China Science and Technology Periodical Database, Wanfang Database, PubMed, Embase, and Web of Science from the date of conception to June 30, 2020. We will manually search for gray literature, such as meeting records and dissertations. Two independent reviewers will screen studies that meet the criteria, extract data, statistical data, and assess the risk of bias. The dichotomous variable will calculate the odds ratio and the corresponding 95% confidence interval. Heterogeneity between included studies will be assessed by heterogeneity χ tests and I index. The forest plots will be used to describe the pooled results. The Begg rank correlation test or Egger linear regression test will be performed to quantize the publication bias.DiscussionThis study will provide high-quality evidence to evaluate the contribution of the ABO blood group in COVID-19 pneumonia infection.Prospero Registration NumberCRD42020195615.

29 keywords...

hide…