• Scott L Weiss, Mark J Peters, AgusMichael S DMSDBoston Children's Hospital and Harvard Medical School, Boston, MA., Waleed Alhazzani, Karen Choong, Heidi R Flori, David P Inwald, Simon Nadel, Mark E Nunnally, Luregn J Schlapbach, Robert C Tasker, Pierre Tissieres, Niranjan Kissoon, and Children’s Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children Taskforce.
• Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.
• Pediatr Crit Care Me. 2020 Nov 1; 21 (11): e1031-e1037.

AbstractSevere acute respiratory syndrome coronavirus 2 is a novel cause of organ dysfunction in children, presenting as either coronavirus disease 2019 with sepsis and/or respiratory failure or a hyperinflammatory shock syndrome. Clinicians must now consider these diagnoses when evaluating children for septic shock and sepsis-associated organ dysfunction. The Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-associated Organ Dysfunction in Children provide an appropriate framework for the early recognition and initial resuscitation of children with sepsis or septic shock caused by all pathogens, including severe acute respiratory syndrome coronavirus 2. However, the potential benefits of select adjunctive therapies may differ from non-coronavirus disease 2019 sepsis.

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