• Tooba Fatima, Sadaf Iftikhar, and Irshad Hussain Qureshi.
• Department of Medicine, King Edward Medical University / Mayo Hospital, Lahore, Pakistan.
• J Coll Physicians Surg Pak. 2020 Aug 1; 30 (8): 853-856.

Objective To find the association between hyperuricemia and ischemic stroke.Study Design Case-control study.Place And Duration Of Study Departments of Medicine and Neurology, Mayo Hospital, Lahore, from October 2015 to September 2016.Methodology A total of 100 patients were recruited in the study. Fifty cases were of acute ischemic stroke and fifty were age- and gender-matched healthy controls. Serum uric acid level was estimted by photometry method at the time of admission. Hyperuricemia was defined as the serum uric acid level of more than 6 mg/dl.Results Mean serum uric acid levels in cases and controls were 5.996 ±1.99 mg/dl and 5.042 ±0.91 mg/dl, respectively. Hyperuricemia was present in 23 (46%) patients with ischemic stroke and in 10 (20%) controls. Among ischemic stroke patients, the frequency of hyperuricemia was significantly higher than in controls (p-value =0.006, Odds Ratio (OR) =3.41.) Conclusion: Serum uric acid was found significantly elevated in ischemic stroke patients versus controls with 3.41 times more risk of having hyperuricemia in ischemic stroke patients. Key Words: Hyperuricemia, Ischemic stroke, Serum uric acid (SUA).

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