• J Coll Physicians Surg Pak · Aug 2020

    Case Reports

    Glyphosate-induced Delayed Pyloric Obstruction, Ulcer and Scar Changes.

    • Jin Yong Hao, Tao Jiang, and Xiao Jun Huang.
    • Department of Gastroenterology, Lanzhou University Second Hospital, Lanzhou, Gansu, China.
    • J Coll Physicians Surg Pak. 2020 Aug 1; 30 (8): 868870868-870.

    AbstractGlyphosate is a widely used herbicide. Acute glyphosate poisoning is not uncommon, mostly caused by a large amount of glyphosate entering the human body in a short time, and the common reason is taking it accidently. The manifestations of acute stage are mainly gastrointestinal reactions. The patient in the present study took glyphosate accidently. In the acute stage, the patient presented with nausea and vomiting, but no gastrointestinal bleeding or perforation was found. Upper gastrointestinal obstruction occurred after two months. Endoscopy revealed no abnormalities in the esophagus, but revealed multiple gastric scar changes, and pyloric obstruction. In addition, active gastric ulcer was also observed. Therefore, the choice of gastric lavage method, avoidance of neutralising acid-base reactions, and the long-term use of acid suppression and mucosal protection therapy may have important therapeutic implications for the repair of gastric mucosa in such cases. Key Words: Glyphosate, Ulceration, Pyloric obstruction.

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