• J Clin Anesth · Feb 2012

    Case Reports

    Successful management of rocuronium-induced anaphylactic reactions with sugammadex: a case report.

    • Takashi Kawano, Takahiko Tamura, Mayuko Hamaguchi, Tomoaki Yatabe, Koichi Yamashita, and Masataka Yokoyama.
    • Department of Anesthesiology and Critical Care Medicine, Kochi Medical School, Kochi, 783-8505, Japan. takashika@kochi-u.ac.jp
    • J Clin Anesth. 2012 Feb 1;24(1):62-4.

    AbstractSugammadex, a new reversal agent for rocuronium, encapsulates the rocuronium molecule and results in rapid reversal of rocuronium-induced neuromuscular blockade. A case in which sugammadex was used to treat an anaphylactic reaction that occurred after rocuronium is presented. The binding/encapsulation of rocuronium by sugammadex may selectively eliminate the antigenic quaternary ammonium activity of circulating rocuronium, and prevent the propagation of rocuronium-induced anaphylaxis.Copyright © 2012 Elsevier Inc. All rights reserved.

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