• Medicine · Feb 2020

    Acupuncture for lumbar disc herniation: Protocol for a systematic review and meta-analysis.

    • Sheng Yuan, Chuyu Huang, Yuanyue Xu, Dong Chen, and Lei Chen.
    • The First Affiliated Hospital of Jinan University.
    • Medicine (Baltimore). 2020 Feb 1; 99 (9): e19117e19117.

    BackgroundAs development of society and change of modern life style, the prevalence of lumbar disc herniation (LDH) has been increasing. Being a major cause of low back pain, sciatica and radicular leg pain, LDH imposes a heavy burden on both individual and society. Because of high surgically intervene rate, non-invasive (non-surgical) treatments are recommended for most cases. Acupuncture has the advantages of low risk, good effect and low cost which has been proven that could alleviate pain while physical therapy plays a major role in the treatment of LDH in the vast majority of countries. The aim of this systematic review is to evaluate the effectiveness and safety of acupuncture for LDH.MethodsRCTs on ACU treating LDH will be searched from the following databases: PubMed, Web of science, EmBase, Cochrane Library, China National Knowledge Infrastructure, Wanfang data, from their inception to May 2020. The primary outcomes are verbal rating scale and functional disability. Two reviewers will independently exclude substandard articles and extract eligible data. The risk of bias will be assessed using the Cochrane Handbook 5.1.0 for Systematic Reviews of Interventions. Egger test will be used to assess the reporting bias. Heterogeneity will be evaluated by the I statistic and Q test. We will conduct the meta-analysis using Stata V12.0 to evaluate the effectiveness of ACU for LDH. In case of high heterogeneity, sensitivity analysis of different items and subgroup analysis will be performed. The Grading of Recommendations Assessment, Development, and Evaluation System will be used to assess the quality of evidence.ResultsThe results of this review will be submitted to a journal for publication.ConclusionThis proposed systematic review will evaluate the effectiveness and safety of acupuncture for LDH.RegistrationPROSPERO (registration number CRD42019148272).

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