• Ir J Med Sci · May 2021

    Atypical presentation of COVID-19 in hospitalised older adults.

    • Jasmine Ming Gan, Jason Kho, Michelle Akhunbay-Fudge, Hwei Ming Choo, Melanie Wright, Farzana Batt, Mandal Amit K J AKJ http://orcid.org/0000-0003-0986-5927 Department of Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Wexham Str, Rahul Chauhan, and Constantinos G Missouris.
    • Department of Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Wexham Street, Slough, UK.
    • Ir J Med Sci. 2021 May 1; 190 (2): 469-474.

    BackgroundIt is increasingly recognised that older patients may not present with typical symptoms of COVID-19.AimsThis study aims to evaluate the incidence, characteristics and clinical outcome of older adults with atypical presentations of COVID-19.MethodsA retrospective analysis of adults ≥ 65 years with confirmed COVID-19 admitted to our institution between 1 March and 24 April 2020 was performed. Patients were categorised into typical or atypical groups based on primary presenting complaint in the community.ResultsOne hundred twenty-two patients (mean age 81 ± 8 years; 62 male) were included. Seventy-three (60%) were categorised into the typical group and 49 (40%) into the atypical group. In the atypical group, common presenting complaints were fall in 18 (36%), reduced mobility or generalised weakness in 18 (36%) and delirium in 11 (22%). Further assessment by paramedics and on admission found 32 (65%) to have typical features of COVID-19, fever being the most common, and 22 (44%) were hypoxic. This subset had worse outcomes than those in the typical group with a mortality rate of 50% versus 38%, respectively, although this was not statistically significant (P = 0.27). No significant difference in mortality or length of hospital stay between the groups was demonstrated.ConclusionOlder patients with atypical presentation of COVID-19 in the community are equally susceptible to poor outcomes. Early detection may improve outcomes and limit community transmission. Primary care practitioners should be vigilant and consider prompt onward referral.

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