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Case Reports
Transbronchial Cryobiopsy for Miliary Tuberculosis Mimicking Hypersensitivity Pneumonitis.
- Shingo Nasu, Kunimitsu Kawahara, Yuki Han, Norio Okamoto, Yoshitaka Tamura, Hidekazu Suzuki, Takayuki Shiroyama, Yumiko Samejima, Tomohiro Kanai, Yoshimi Noda, Ayako Tanaka, Naoko Morishita, Kayo Ueda, Shoji Hashimoto, Tomonori Hirashima, and Takayuki Nagai.
- Department of Thoracic Oncology, Osaka Habikino Medical Center, Japan.
- Intern. Med. 2021 Feb 1; 60 (3): 445-448.
AbstractMiliary tuberculosis is a potentially lethal type of tuberculosis that results from the hematogenous dissemination of Mycobacterium tuberculosis bacilli. We herein describe the case of a 34-year-old man that presented with a one-month history of cough and fever, while his sputum smear results were negative. Chest computed tomography revealed bilateral centrilobular ground-glass opacification (GGO), suggestive of hypersensitivity pneumonitis; thus, bronchoscopy was performed. Cryobiopsy specimens revealed necrotic granulomas. A re-examination of sputum after bronchoscopy identified Mycobacterium tuberculosis, and miliary tuberculosis was diagnosed. A cryobiopsy might be useful for diagnosing miliary tuberculosis pathologically, particularly when miliary nodules may be masked by GGO.
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