• Internal medicine · Feb 2021

    Secondary Cardiac Lymphoma Presenting as Sick Sinus Syndrome and Atrial Fibrillation Which Required Leadless Pacemaker Implantation.

    • Shun Kondo, Hiroyuki Osanai, Yusuke Sakamoto, Hiroto Uno, Kensuke Tagahara, Hirotaka Hosono, Shun Miyamoto, Shotaro Hiramatsu, Hikari Matsumoto, Teruhiro Sakaguchi, Takahiro Kanbara, Yoshihito Nakashima, Hiroshi Asano, and Masayoshi Ajioka.
    • Department of Cardiology, Tosei General Hospital, Japan.
    • Intern. Med. 2021 Feb 1; 60 (3): 431434431-434.

    AbstractCardiac involvement of malignant lymphoma is relatively common, although such a phenomenon has subclinical manifestations that are difficult to detect. We herein describe a patient with atrial fibrillation and sick sinus syndrome as the main symptoms. Computed tomography showed a mass in the right atrium extending into the superior vena cava (SVC). We implanted the patient with a leadless pacemaker. Transvenous biopsy revealed a diffuse large B-cell lymphoma. The patient was treated successfully with chemotherapy including rituximab. This case suggested that cardiac lymphoma may cause sick sinus syndrome, and leadless pacemaker implantation is a safe treatment option in patients with partial SVC obstruction.

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