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- Tasuku Hara, Kohei Oka, Naoto Iwai, Yutaka Inada, Toshifumi Tsuji, Takashi Okuda, Akihiro Nagata, Toshiyuki Komaki, and Keizo Kagawa.
- Department of Gastroenterology and Hepatology, Fukuchiyama City Hospital, Japan.
- Intern. Med. 2021 Feb 1; 60 (3): 417-421.
AbstractA 54-year-old woman underwent chemotherapy including rituximab and autologous peripheral blood stem cell transplantation (auto-PBSCT) for diffuse large B-cell lymphoma. Before the treatment, she exhibited a resolved hepatitis B virus (HBV) infection. She was diagnosed with HBV reactivation based on positive serum HBV-DNA test results, 55 months after her last treatment. Subsequently, he was treated with tenofovir alafenamide fumarate (TAF) therapy and her liver function improved. Patients undergoing chemotherapy including rituximab and auto-PBSCT are at a high risk of HBV reactivation. In such cases, careful and long-term observations may be required to detect HBV reactivation.
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