• Fivzia Herekar, Sundus Iftikhar, Ahsana Nazish, and Sabeen Rehman.
• Fivzia Herekar, FCPS (Infectious Diseases), Department of Internal Medicine, Indus Hospital Research Center, The Indus Hospital, Karachi, Pakistan.
• Pak J Med Sci. 2020 Jan 1; 36 (1): S33-S37.

Background And ObjectiveMalaria is an arthropod-borne infectious disease transmitted by the mosquito Anopheles and claims millions of lives globally every year. Reasons for failure to eradicate this disease are multifactorial. The seasonality of the malaria is principally determined by climatic factors conducive for breeding of the vector. We aimed to study the relationship between climatic variability and the seasonality of malaria over an eight-year duration.MethodsThis was a retrospective medical chart review of 8,844 confirmed cases of malaria which presented to The Indus Hospital, Karachi from January 2008 to November 2015. Cases were plotted against meteorological data for Karachi to elicit monthly variation.ResultsA secular incline and seasonality in malaria cases over the duration of eight years was seen. More cases were reported in the summer, rainy season compared with the other three seasons in each year. There was significant association with specific climate variables such as temperature, moisture, and humidity.ConclusionThere is a marked seasonal variation of malaria in Karachi, influenced by various environmental factors. Identification of the 'the concentrated period' of malaria can be helpful for policymakers to deploy malaria control interventions.Copyright: © Pakistan Journal of Medical Sciences.

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