• Tauseef Ahmad, Adeel Khoja, Naveed Haroon Rashid, and Muhammad Areeb Ashfaq.
• Dr. Tauseef Ahmad, FCPS, Assistant Professor of Medicine/Endocrinology, Dr. Ziauddin University Hospital, Karachi, Pakistan.
• Pak J Med Sci. 2018 Sep 1; 34 (5): 1146-1151.

ObjectiveTo determine the outcome of patients receiving radioactive iodine therapy for toxic nodular goiter coming to Aga Khan University Hospital Karachi.MethodsA total of 89 patients who visited the outpatient department of Aga Khan University Hospital from January 2010 to August 2017 were recruited for the study. Toxic nodular goiter was diagnosed on the basis of having hot nodule on thyroid scan with low TSH and high FT4/T4. Other demographic and laboratory data were also recorded.ResultsEighty nine patients with toxic nodular goiter received a dose range from 10 to 30mCi RAI. Six months after RAI, 36.2% became hypothyroid, 38.5% became euthyroid while 25.3% remained hyperthyroid. Thyroid outcome at 3 months were correlating with 6 months results.ConclusionRadioactive iodine therapy is a safe and effective way of treating toxic nodular goiter which usually results in cure of hyperthyroidism in majority of patients.

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