• Pak J Med Sci · Jul 2019

    Review

    Impact of environmental pollution, dietary factors and diabetes mellitus on Autism Spectrum Disorder (ASD).

    • Abdulrahman Mohammed Alhowikan, Laila Yousef Al-Ayadhi, and Dost Muhammad Halepoto.
    • Abdulrahman Mohammed Alhowikan, PhD. Department of Physiology, Faculty of Medicine, King Saud University, P O Box 2925, Riyadh 11461 and Saudi Arabia.
    • Pak J Med Sci. 2019 Jul 1; 35 (4): 117911841179-1184.

    AbstractAutism spectrum disorder (ASD) is complex neurodevelopmental condition described by impairments in three main behavioral areas: social deficits, impaired communication, and repetitive behaviors. Despite many years of vast study, the causes of ASD are still unknown. Various risk factors including genetic, infectious, metabolic and immunological have been investigated however, environmental, nutritional and diabetes related risk factors have not received sufficient attention. This study has provided an insight into the comprehensive interaction between environmental pollution, dietary factors and diabetes mellitus that could lead to the advancement of this debilitating neurodevelopment disorder. The literature search was done using PubMed and Google Scholar databases up to October 2018. Key words "Environmental Pollution", "Nutritional Factors", "Diabetes Mellitus", "Autism Spectrum Disorder" were selected.

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