• Mayo Clinic proceedings · Oct 2020

    Review

    Common Myths and Misconceptions That Sidetrack Parkinson Disease Treatment, to the Detriment of Patients.

    • J Eric Ahlskog.
    • Department of Neurology, Mayo Clinic, Rochester, MN. Electronic address: eahlskog@mayo.edu.
    • Mayo Clin. Proc. 2020 Oct 1; 95 (10): 2225-2234.

    AbstractParkinson disease symptoms become apparent when there has been substantial loss of brain dopamine. That is the consequence of the slow progression of the Lewy body neurodegenerative process. Replenishment of brain dopamine with levodopa therapy dates back approximately a half century and continues to be the most efficacious symptomatic treatment. Understanding the fundamentals of levodopa treatment is crucial to therapeutic success. Various myths over the years have sabotaged treatment outcomes and have discouraged primary care physicians from managing patients with Parkinson disease. That is unfortunate because in some regions, neurologists, and in particular movement specialists, are in short supply. The long history of these persistent levodopa myths and the counterarguments are the focus of this article.Copyright © 2020 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

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