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- Junya Tanabe, Nobuhide Watanabe, Akihiro Endo, Taichi Nagami, Satoshi Inagaki, and Kazuaki Tanabe.
- Division of Cardiology, Shimane University Faculty of Medicine, Japan.
- Intern. Med. 2021 Feb 15; 60 (4): 569-573.
AbstractWe herein report the case of a 75-year-old man with asymptomatic immune checkpoint inhibitor (ICI)-associated myocarditis diagnosed on the basis of elevated levels of creatine kinase (CK), CK-myocardial band and troponin I (TNI). He was suspected of being complicated with myasthenia gravis (MG). High-dose prednisolone (PSL) is associated with a risk of MG exacerbation; therefore, PSL therapy was gradually increased from 5 mg/day to 20 mg/day, which resulted in the normalization of the TNI level, and no PSL-related side effects occurred. MG easily complicates myocarditis as an immune-related adverse event; thus, the treatment plan should be carefully considered.
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