• J Coll Physicians Surg Pak · Sep 2020

    Diagnostic Performance of One-hour Delta High Sensitive Troponin in Acute Coronary Syndrome.

    • Bahadir Caglar and Suha Serin.
    • Department of Emergency Medicine, Balikesir University, Turkey.
    • J Coll Physicians Surg Pak. 2020 Sep 1; 30 (9): 906-911.

    ObjectiveTo determine the impact of an increase in the level of high sensitivite (HS) troponin-I between the time of Emergency Department (ED) arrival and one-hour after arrival (0h-1h), and between the time of ED arrival and three hours after arrival (0h-3h), upon the diagnostic performance of HS troponin-I to correctly diagnose AMI.Study DesignDescriptive, analytical study.Place And Duration Of StudyFethi Sekin City Hospital, Elazig, Turkey from January to June 2019.MethodologyPatients presenting with chest pain were included in the study. The delta HS Troponin I (0h-1h) and delta HS Troponin I (0h-3h) values of the patients were calculated as percentage changes. These values were statistically compared between those who were diagnosed with acute myocardial infarction (AMI).ResultsThe evaluation was performed on 114 patients. Delta HS Troponin I levels were examined, a change of >20% was observed in 48 patients (42.1%) for the 0-1 hr interval. Of the 20 patients ultimately diagnosed with an AMI, 16 (80%) had such a change at this time (p <0.001). For 0-3 hr interval, a change of HS Troponin-I of >20% was observed in 52 patients (45.6%); and 17 of 20 AMI patients with an AMI were detected by such a change (p<0.001).ConclusionDelta HS troponin I value in the first hour was nearly as sensitive for detection of an AMI as was delta HS Troponin I third-hour value. Key Words: Troponin, Myocardial infarction, Acute coronary syndrome.

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