• Am. J. Obstet. Gynecol. · Jan 2011

    Randomized Controlled Trial

    Does midtrimester Nugent score or high vaginal pH predict gestational age at delivery in women at risk for recurrent preterm birth?

    • Dana Figueroa, Melissa S Mancuso, Jeff M Szychowski, Merri Maddox Paden, John Owen, and Vaginal Ultrasound Trial Consortium.
    • Department of Obstetrics and Gynecology, University of Alabama at Birmingham, USA.
    • Am. J. Obstet. Gynecol. 2011 Jan 1; 204 (1): 46.e1-4.

    ObjectiveTo estimate whether bacterial vaginosis, as defined by either Nugent score or vaginal pH, predicts gestational age at delivery in women at risk for recurrent preterm birth.Study DesignPlanned secondary analysis of a randomized cerclage trial in women with prior spontaneous preterm birth 17⁰(/)⁷-33⁶(/)⁷ weeks. Vaginal Gram stain and pH were collected at the initial study visit. Women not assigned to cerclage, either because they did not experience cervical shortening <25 mm or because they were randomly assigned to no cerclage, were studied.ResultsSeven hundred eighty-six women had complete delivery gestational age, Gram stain, and pH results. The diagnosis of bacterial vaginosis by either Nugent score ≥ 7 or by pH ≥ 5 was not associated with earlier birth.ConclusionThe presence of bacterial vaginosis at 16-21⁶(/)⁷ weeks does not predict gestational age at birth in women at risk for recurrent preterm birth.Copyright © 2011 Mosby, Inc. All rights reserved.

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