• BJOG · Jul 2013

    Metabolic syndrome and the risk for recurrent pre-eclampsia: a retrospective cohort study.

    • E Stekkinger, Rr Scholten, M J van der Vlugt, A P J van Dijk, M C H Janssen, and M E A Spaanderman.
    • Department of Obstetrics and Gynaecology, Deventer Hospital, Deventer, the Netherlands. e.stekkinger@dz.nl
    • BJOG. 2013 Jul 1; 120 (8): 979-86.

    ObjectiveTo compare the prevalence of recurrent pre-eclampsia between women who have and do not have metabolic syndrome when non-pregnant.DesignRetrospective cohort study.SettingThree tertiary referral hospitals in the Netherlands.PopulationFormerly pre-eclamptic women.MethodsThe presence or absence of metabolic syndrome was assessed in 480 women at least 6 months after their first pre-eclamptic pregnancy using World Health Organization criteria. We compared the prevalence of recurrent pre-eclampsia in the subsequent pregnancy, calculating odds ratios (OR), adjusted for confounders.Main Outcome MeasureRecurrence of pre-eclampsia in the subsequent pregnancy.ResultsSubsequent pregnancy outcome data were available for 197 women. Forty women had metabolic syndrome after previous pregnancy (20%). The prevalence of recurrent pre-eclampsia was 18/40 (45%) in women with metabolic syndrome versus 27/157 (17%) in women without metabolic syndrome; OR 3.94 (95% confidence interval [CI] 1.86-8.33, adjusted OR 3.77 (95% CI 1.61-8.81). The risk of recurrent pre-eclampsia increased with each extra component of the metabolic syndrome from 11.8% for absent components up to 43.9% for three or more (P for trend < 0.001).ConclusionsInterpregnancy metabolic syndrome predisposes to recurrent pre-eclampsia.© 2013 The Authors BJOG An International Journal of Obstetrics and Gynaecology © 2013 RCOG.

      Pubmed     Free full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…