• J. Thromb. Haemost. · Jul 2018

    Meta Analysis

    Reduced-dose direct oral anticoagulants in the extended treatment of venous thromboembolism: a systematic review and meta-analysis.

    • L Vasanthamohan, K Boonyawat, C Chai-Adisaksopha, and M Crowther.
    • Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
    • J. Thromb. Haemost. 2018 Jul 1; 16 (7): 1288-1295.

    AbstractEssentials In venous thromboembolism (VTE), benefits of extended treatment are balanced by bleeding risks. This is a meta-analysis of reduced-dose direct oral anticoagulants (DOACs) in extended treatment. Reduced-dose DOACs are as effective as full anticoagulation with bleeding risks similar to placebo. Reduced-dose DOACs are an attractive option for patients in the extended phase of VTE treatment.© 2018 International Society on Thrombosis and Haemostasis.

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