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J. Thromb. Haemost. · Jul 2018
Meta AnalysisReduced-dose direct oral anticoagulants in the extended treatment of venous thromboembolism: a systematic review and meta-analysis.
- L Vasanthamohan, K Boonyawat, C Chai-Adisaksopha, and M Crowther.
- Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
- J. Thromb. Haemost. 2018 Jul 1; 16 (7): 1288-1295.
AbstractEssentials In venous thromboembolism (VTE), benefits of extended treatment are balanced by bleeding risks. This is a meta-analysis of reduced-dose direct oral anticoagulants (DOACs) in extended treatment. Reduced-dose DOACs are as effective as full anticoagulation with bleeding risks similar to placebo. Reduced-dose DOACs are an attractive option for patients in the extended phase of VTE treatment.© 2018 International Society on Thrombosis and Haemostasis.
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