• J Am Dent Assoc · Aug 1987

    Comparative Study Clinical Trial Controlled Clinical Trial

    Efficacy of diphenhydramine hydrochloride for local anesthesia before oral surgery.

    • W J Gallo and E Ellis.
    • J Am Dent Assoc. 1987 Aug 1; 115 (2): 263-6.

    AbstractThe efficacy of diphenhydramine hydrochloride with epinephrine was tested against lidocaine with epinephrine in a double-blind study. Patients with allergic reactions to general local anesthetics were safely and effectively treated with diphenhydramine hydrochloride as an anesthetic alternative.

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