• Resp Res · Apr 2020

    Letter Case Reports

    The unsynchronized changes of CT image and nucleic acid detection in COVID-19: reports the two cases from Gansu, China.

    • Jing Gao, Jun-Qiang Liu, Heng-Jun Wen, Hua Liu, Wei-Dong Hu, Xia Han, Chuan-Xing Li, and Xiao-Jun Wang.
    • Department of Respiratory Medicine, Gansu Provincial Hospital, No 204 Donggang West Road, Lanzhou, 730000, China.
    • Resp Res. 2020 Apr 22; 21 (1): 96.

    AbstractThe novel coronavirus disease (COVID-19) outbreak started in December 2019 in Wuhan, China, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The CT image is used to assess the disease progress, whereas the continued two times of negative results from SARS-CoV-2 nucleic acid detection had been considered as a criterion for ending antiviral treatment. We compared the two COVID-19 cases with similar backgrounds and CT image repeated intervals under treatment. Our report highlighted the unsynchronized expression in the changes of CT image and nucleic acid detection in COVID-19, and lasting positive nucleic acid test result in patients recovered from pneumonia. It may be contributed to recognize the disease and improve prevention.

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