• Xixiong Wang, Cunren Chen, Buping Zheng, Xiaolong Yang, Xiaoxin Zhang, and Chenchen Yang.
• Department of surgical oncology, Boao Evergrande International Hospital, Qionghai.
• Medicine (Baltimore). 2020 Oct 23; 99 (43): e22755e22755.

BackgroundThe comparative efficacy of bariatric surgical procedures for type 2 diabetes mellitus (T2DM) has not been completely elucidated. To investigate this question, we conduct a systematic review and network meta-analysis.MethodsThe protocol followed preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) checklist. Two review authors will independently search the PubMed, Embase (Ovid), and the Cochrane Central Register of Controlled Trials databases. The primary outcome is T2DM remission. The secondary outcomes include BMI, HbA1c (%), and percentage excess weight loss (% EWL). Results from the network meta-analysis will be presented as summary relative effect sizes (WMD or RR) and relative 95% CIs for each possible pair of treatments. Outcomes will be combined based on different periods of follow-up (12 months, 36 months, and 60 months).ResultsThe results will provide useful information about the efficacy of bariatric surgical procedures in patients with T2DM.ConclusionThe findings of the study will be disseminated through peer-reviewed journal.Inplasy Registration NumberINPLASY202050053.

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